{"product_id":"reed-biotech-hla-dmbeta-polyclonal-antibody-ra25964","title":"HLA-DMβ Polyclonal Antibody","description":"\u003cp\u003emajor histocompatibility complex, class II, DM beta(HLA-DMB) Homo sapiens HLA-DMB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta (DMB) chain, both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP (class II-associated invariant chain peptide) molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. [provided by RefSeq, Jul 2008],\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50 µL","offer_id":57249761263956,"sku":"ABM5030358-1","price":137.0,"currency_code":"USD","in_stock":true},{"title":"100 µL","offer_id":57249761296724,"sku":"ABM5030358-2","price":184.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Antibody.webp?v=1790791467","url":"https:\/\/www.abmium.com\/de\/products\/reed-biotech-hla-dmbeta-polyclonal-antibody-ra25964","provider":"ABMIUM","version":"1.0","type":"link"}