{"product_id":"reed-biotech-cd35-polyclonal-antibody-ra23047","title":"CD35 Polyclonal Antibody","description":"\u003cp\u003ecomplement C3b\/C4b receptor 1 (Knops blood group)(CR1) Homo sapiens This gene is a member of the receptors of complement activation (RCA) family and is located in the \u0026amp;apos;cluster RCA\u0026amp;apos; region of chromosome 1. The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells. The Knops blood group system is a system of antigens located on this protein. The protein mediates cellular binding to particles and immune complexes that have activated complement. Decreases in expression of this protein and\/or mutations in its gene have been associated with gallbladder carcinomas, mesangiocapillary glomerulonephritis, systemic lupus erythematosus and sarcoidosis. Mutations in this gene have also been associated with a reduction in Plasmodium falciparum rosetting, conferring protection against severe malaria. Alternate allele-specific splice variants\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50 µL","offer_id":57251028009300,"sku":"ABM5027441-1","price":113.4,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":57251028042068,"sku":"ABM5027441-2","price":153.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Antibody.webp?v=1790791467","url":"https:\/\/www.abmium.com\/de\/products\/reed-biotech-cd35-polyclonal-antibody-ra23047","provider":"ABMIUM","version":"1.0","type":"link"}