{"product_id":"reed-biotech-ar-alpha1b-polyclonal-antibody-ra22110","title":"AR-α1B Polyclonal Antibody","description":"\u003cp\u003eadrenoceptor alpha 1B(ADRA1B) Homo sapiens Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq\/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region. [provided by RefSeq, Jul 2008],\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50 µL","offer_id":57250530263380,"sku":"ABM5026504-1","price":113.4,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":57250530296148,"sku":"ABM5026504-2","price":153.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Antibody.webp?v=1790791467","url":"https:\/\/www.abmium.com\/de\/products\/reed-biotech-ar-alpha1b-polyclonal-antibody-ra22110","provider":"ABMIUM","version":"1.0","type":"link"}