{"product_id":"reed-biotech-acy1-polyclonal-antibody-ra31006","title":"ACY1 Polyclonal Antibody","description":"\u003cp\u003eaminoacylase 1(ACY1) Homo sapiens This gene encodes a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and an acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. This gene is located on chromosome 3p21.1, a region reduced to homozygosity in small-cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart, and this enzyme is the first member of a new family of zinc-binding enzymes. Mutations in this gene cause aminoacylase-1 deficiency, a metabolic disorder characterized by central nervous system defects and increased urinary excretion of N-acetylated amino acids. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription als\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50 µL","offer_id":57249732919636,"sku":"ABM5035400-1","price":113.4,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":57249732952404,"sku":"ABM5035400-2","price":153.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Antibody.webp?v=1790791467","url":"https:\/\/www.abmium.com\/de\/products\/reed-biotech-acy1-polyclonal-antibody-ra31006","provider":"ABMIUM","version":"1.0","type":"link"}