{"product_id":"rabbit-polyclonal-antibody-to-usp3-p42651","title":"Anti-USP3 Rabbit Polyclonal Antibody","description":"\u003cp\u003eDeubiquitinating enzyme tethered to the mitochondrial outer membrane that acts as a key inhibitor of mitophagy by counteracting the action of parkin (PRKN): hydrolyzes ubiquitin attached by parkin on target proteins, such as RHOT1\/MIRO1 and TOMM20, thereby blocking parkin's ability to drive mitophagy. Preferentially cleaves 'Lys-6'- and 'Lys-11'-linked polyubiquitin chains, 2 types of linkage that participate in mitophagic signalling. Does not cleave efficiently polyubiquitin phosphorylated at 'Ser-65'.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58167001776468,"sku":"ABM419688-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58167001809236,"sku":"ABM419688-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58167001842004,"sku":"ABM419688-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/de\/products\/rabbit-polyclonal-antibody-to-usp3-p42651","provider":"ABMIUM","version":"1.0","type":"link"}