{"product_id":"rabbit-polyclonal-antibody-to-upf3b-p30523","title":"Anti-UPF3B Rabbit Polyclonal Antibody","description":"\u003cp\u003e\u003cstrong\u003eUPF3B\u003c\/strong\u003e is involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by associating with the nuclear exon junction complex (EJC) and serving as link between the EJC core and NMD machinery. Recruits UPF2 at the cytoplasmic side of the nuclear envelope and the subsequent formation of an UPF1-UPF2-UPF3 surveillance complex (including UPF1 bound to release factors at the stalled ribosome) is believed to activate NMD. In cooperation with UPF2 stimulates both ATPase and RNA helicase activities of UPF1.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58031282848084,"sku":"ABM413756-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58031282880852,"sku":"ABM413756-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58031282913620,"sku":"ABM413756-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/de\/products\/rabbit-polyclonal-antibody-to-upf3b-p30523","provider":"ABMIUM","version":"1.0","type":"link"}