{"product_id":"rabbit-polyclonal-antibody-to-tradd-p31021","title":"Anti-TRADD Rabbit Polyclonal Antibody","description":"\u003cp\u003eAdapter molecule for TNFRSF1A\/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A\/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B. The nuclear form acts as a tumour suppressor by preventing ubiquitination and degradation of isoform p19ARF\/ARF of CDKN2A by TRIP12: acts by interacting with TRIP12, leading to disrupt interaction between TRIP12 and isoform p19ARF\/ARF of CDKN2A.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58031409070420,"sku":"ABM414236-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58031409103188,"sku":"ABM414236-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58031409135956,"sku":"ABM414236-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/de\/products\/rabbit-polyclonal-antibody-to-tradd-p31021","provider":"ABMIUM","version":"1.0","type":"link"}