{"product_id":"rabbit-polyclonal-antibody-to-tbcd7-p30584","title":"Anti-TBCD7 Rabbit Polyclonal Antibody","description":"\u003cp\u003eNon-catalytic component of the TSC-TBC complex, a multiprotein complex that acts as a negative regulator of the canonical mTORC1 complex, an evolutionarily conserved central nutrient sensor that stimulates anabolic reactions and macromolecule biosynthesis to promote cellular biomass generation and growth. The TSC-TBC complex acts as a GTPase-activating protein (GAP) for the small GTPase RHEB, a direct activator of the protein kinase activity of mTORC1. In absence of nutrients, the TSC-TBC complex inhibits mTORC1, thereby preventing phosphorylation of ribosomal protein S6 kinase (RPS6KB1 and RPS6KB2) and EIF4EBP1 (4E-BP1) by the mTORC1 signalling.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58031292055892,"sku":"ABM413813-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58031292088660,"sku":"ABM413813-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58031292121428,"sku":"ABM413813-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/de\/products\/rabbit-polyclonal-antibody-to-tbcd7-p30584","provider":"ABMIUM","version":"1.0","type":"link"}