{"product_id":"rabbit-polyclonal-antibody-to-spdya-p34222","title":"Anti-SPDYA Rabbit Polyclonal Antibody","description":"\u003cp\u003e\u003cstrong\u003eSPDYA\u003c\/strong\u003e regulates the G1\/S phase transition of the cell cycle by binding and activating CDK1 and CDK2. SPDYA contributes to CDK2 activation without promoting CDK2 phosphorylation, by inducing a conformation change of the CDK2 T-loop that obstructs the substrate-binding cleft prior to kinase activation. SPDYA mediates cell survival during the DNA damage process through activation of CDK2.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58157418840404,"sku":"ABM417049-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58157418873172,"sku":"ABM417049-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58157418905940,"sku":"ABM417049-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/de\/products\/rabbit-polyclonal-antibody-to-spdya-p34222","provider":"ABMIUM","version":"1.0","type":"link"}