{"product_id":"rabbit-polyclonal-antibody-to-smad3-s208-p30601","title":"Anti-SMAD3-S208 Rabbit Polyclonal Antibody","description":"\u003cp\u003eReceptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. SMAD3 binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD3\/SMAD4 complex, activates transcription. Also can form a SMAD3\/SMAD4\/JUN\/FOS complex at the AP-1\/SMAD site to regulate TGF-beta-mediated transcription.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58031294677332,"sku":"ABM413830-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58031294710100,"sku":"ABM413830-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58031294742868,"sku":"ABM413830-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/de\/products\/rabbit-polyclonal-antibody-to-smad3-s208-p30601","provider":"ABMIUM","version":"1.0","type":"link"}