{"product_id":"rabbit-polyclonal-antibody-to-samhd1-p31829","title":"Anti-SAMHD1 Rabbit Polyclonal Antibody","description":"\u003cp\u003e\u003cstrong\u003eSAMHD1\u003c\/strong\u003e is a protein that acts both as a host restriction factor involved in defense response to virus and as a regulator of DNA end resection at stalled replication forks. SAMHD1 has deoxynucleoside triphosphate (dNTPase) activity, which is required to restrict infection by viruses, such as HIV-1: dNTPase activity reduces cellular dNTP levels to levels too low for retroviral reverse transcription to occur, blocking early-stage virus replication in dendritic and other myeloid cells. Likewise, suppresses LINE-1 retrotransposon activity.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58035568738644,"sku":"ABM414988-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58035568771412,"sku":"ABM414988-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58035568804180,"sku":"ABM414988-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/de\/products\/rabbit-polyclonal-antibody-to-samhd1-p31829","provider":"ABMIUM","version":"1.0","type":"link"}