{"product_id":"rabbit-polyclonal-antibody-to-rnf31-p33470","title":"Anti-RNF31 Rabbit Polyclonal Antibody","description":"\u003cp\u003e\u003cstrong\u003eRNF31\u003c\/strong\u003e is an E3 ubiquitin-protein ligase component of the LUBAC complex which conjugates linear ('Met-1'-linked) polyubiquitin chains to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation. LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and the JNK signalling pathways. Linear ubiquitination mediated by the LUBAC complex interferes with TNF-induced cell death and thereby prevents inflammation.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58157099942228,"sku":"ABM416360-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58157099974996,"sku":"ABM416360-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58157100007764,"sku":"ABM416360-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/de\/products\/rabbit-polyclonal-antibody-to-rnf31-p33470","provider":"ABMIUM","version":"1.0","type":"link"}