{"product_id":"rabbit-polyclonal-antibody-to-rest-p06226","title":"Anti-REST Rabbit Polyclonal Antibody","description":"\u003cp\u003e\u003cstrong\u003eREST\u003c\/strong\u003e is a transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells. Restricts the expression of neuronal genes by associating with two distinct corepressors, SIN3A and RCOR1, which in turn recruit histone deacetylase to the promoters of REST-regulated genes. REST mediates repression by recruiting the BHC complex at RE1\/NRSE sites which acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58006605103444,"sku":"ABM402625-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58006605136212,"sku":"ABM402625-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58006605168980,"sku":"ABM402625-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/de\/products\/rabbit-polyclonal-antibody-to-rest-p06226","provider":"ABMIUM","version":"1.0","type":"link"}