{"product_id":"rabbit-polyclonal-antibody-to-p2ry8-p43236","title":"Anti-P2RY8 Rabbit Polyclonal Antibody","description":"\u003cp\u003e\u003cstrong\u003eP2RY8\u003c\/strong\u003e is a G protein-coupled receptor for S-geranylgeranyl-glutathione (GGG), an endogenous metabolite present in lymphoid tissues. Couples the binding of GGG to the activation of GNA13 and downstream repression of AKT activation in lymphocytes defining their positioning and growth within lymphoid organs. In lymphoid follicles, confines B cells and follicular helper T cells in germinal centers (GCs) in response to GGG local gradients established by GGT5 (via GGG catabolism) and ABCC1 (via extracellular transport) with lower concentrations of GGG found in the follicular dendritic cell network region around which germinal centers are formed.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58167501717844,"sku":"ABM420164-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58167501750612,"sku":"ABM420164-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58167501783380,"sku":"ABM420164-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/de\/products\/rabbit-polyclonal-antibody-to-p2ry8-p43236","provider":"ABMIUM","version":"1.0","type":"link"}