{"product_id":"rabbit-polyclonal-antibody-to-nnmt-p33590","title":"Anti-NNMT Rabbit Polyclonal Antibody","description":"\u003cp\u003ecatalyses the N-methylation of nicotinamide using the universal methyl donor S-adenosyl-L-methionine to form N1-methylnicotinamide and S-adenosyl-L-homocysteine, a predominant nicotinamide\/vitamin B3 clearance pathway. NNMT plays a central role in regulating cellular methylation potential, by consuming S-adenosyl-L-methionine and limiting its availability for other methyltransferases. Actively mediates genome-wide epigenetic and transcriptional changes through hypomethylation of repressive chromatin marks, such as H3K27me3.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58157117309268,"sku":"ABM416468-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58157117342036,"sku":"ABM416468-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58157117374804,"sku":"ABM416468-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/de\/products\/rabbit-polyclonal-antibody-to-nnmt-p33590","provider":"ABMIUM","version":"1.0","type":"link"}