{"product_id":"rabbit-polyclonal-antibody-to-mitf-ab-180-73-p41648","title":"Anti-MITF (Ab-180\/73) Rabbit Polyclonal Antibody","description":"\u003cp\u003e\u003cstrong\u003eMITF\u003c\/strong\u003e is a transcription factor that acts as a master regulator of melanocyte survival and differentiation as well as melanosome biogenesis. MITF binds to M-boxes (5'-TCATGTG-3') and symmetrical DNA sequences (E-boxes) (5'-CACGTG-3') found in the promoter of pigmentation genes, such as tyrosinase (TYR). MITF is involved in the cellular response to amino acid availability by acting downstream of MTOR: in the presence of nutrients, MITF phosphorylation by MTOR promotes its inactivation.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58162521440596,"sku":"ABM418805-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58162521473364,"sku":"ABM418805-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58162521506132,"sku":"ABM418805-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/de\/products\/rabbit-polyclonal-antibody-to-mitf-ab-180-73-p41648","provider":"ABMIUM","version":"1.0","type":"link"}