{"product_id":"rabbit-polyclonal-antibody-to-lmtk3-p43165","title":"Anti-LMTK3 Rabbit Polyclonal Antibody","description":"\u003cp\u003e\u003cstrong\u003eLMTK3\u003c\/strong\u003e is a protein kinase which phosphorylates ESR1 (in vitro) and protects it against proteasomal degradation. LMTK3 may also regulate ESR1 levels indirectly via a PKC-AKT-FOXO3 pathway where it decreases the activity of PKC and the phosphorylation of AKT, thereby increasing binding of transcriptional activator FOXO3 to the ESR1 promoter and increasing ESR1 transcription. LMTK3 is involved in endocytic trafficking of N-methyl-D-aspartate receptors (NMDAR) in neurons.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58167468786004,"sku":"ABM420105-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58167468818772,"sku":"ABM420105-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58167468851540,"sku":"ABM420105-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/de\/products\/rabbit-polyclonal-antibody-to-lmtk3-p43165","provider":"ABMIUM","version":"1.0","type":"link"}