{"product_id":"rabbit-polyclonal-antibody-to-klhl3-p42129","title":"Anti-KLHL3 Rabbit Polyclonal Antibody","description":"\u003cp\u003eSubstrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a regulator of ion transport in the distal nephron. The BCR(KLHL3) complex acts by mediating ubiquitination and degradation of WNK1 and WNK4, two activators of Na-Cl cotransporter SLC12A3\/NCC in distal convoluted tubule cells of kidney, thereby regulating NaCl reabsorption. The BCR(KLHL3) complex also mediates ubiquitination and degradation of WNK3.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58163201638740,"sku":"ABM419204-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58163201671508,"sku":"ABM419204-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58163201704276,"sku":"ABM419204-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/de\/products\/rabbit-polyclonal-antibody-to-klhl3-p42129","provider":"ABMIUM","version":"1.0","type":"link"}