{"product_id":"rabbit-polyclonal-antibody-to-ilk-p07381","title":"Anti-ILK Rabbit Polyclonal Antibody","description":"\u003cp\u003eScaffold protein which mediates protein-protein interactions during a range of cellular events including focal adhesion assembly, cell adhesion and cell migration. ILK regulates integrin-mediated signal transduction by contributing to inside-out integrin activation. Recruits PARVA and LIMS1\/PITCH to form the heterotrimeric IPP (ILK-PINCH-PARVIN) complex which binds to F-actin via the C-terminal tail of LIMS1 and the N-terminal region of PARVA, promoting F-actin filament bundling, a process required to generate force for actin cytoskeleton reorganization and subsequent dynamic cell adhesion events such as cell spreading and migration.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58006691578196,"sku":"ABM403182-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58006691610964,"sku":"ABM403182-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58006691643732,"sku":"ABM403182-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/de\/products\/rabbit-polyclonal-antibody-to-ilk-p07381","provider":"ABMIUM","version":"1.0","type":"link"}