{"product_id":"rabbit-polyclonal-antibody-to-il2-p30423","title":"Anti-IL2 Rabbit Polyclonal Antibody","description":"\u003cp\u003e\u003cstrong\u003eIL2\u003c\/strong\u003e is a cytokine produced by activated CD4-positive helper T-cells and to a lesser extend activated CD8-positive T-cells and natural killer (NK) cells that plays pivotal roles in the immune response and tolerance. IL2 binds to a receptor complex composed of either the high-affinity trimeric IL-2R (IL2RA\/CD25, IL2RB\/CD122 and IL2RG\/CD132) or the low-affinity dimeric IL-2R (IL2RB and IL2RG). Interaction with the receptor leads to oligomerization and conformation changes in the IL-2R subunits resulting in downstream signalling starting with phosphorylation of JAK1 and JAK3.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58031258698068,"sku":"ABM413662-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58031258730836,"sku":"ABM413662-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58031258763604,"sku":"ABM413662-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/de\/products\/rabbit-polyclonal-antibody-to-il2-p30423","provider":"ABMIUM","version":"1.0","type":"link"}