{"product_id":"rabbit-polyclonal-antibody-to-il-10-p43301","title":"Anti-IL-10 Rabbit Polyclonal Antibody","description":"\u003cp\u003eMajor immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58167534453076,"sku":"ABM420212-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58167534485844,"sku":"ABM420212-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58167534518612,"sku":"ABM420212-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/de\/products\/rabbit-polyclonal-antibody-to-il-10-p43301","provider":"ABMIUM","version":"1.0","type":"link"}