{"product_id":"rabbit-polyclonal-antibody-to-fbxl2-p34612","title":"Anti-FBXL2 Rabbit Polyclonal Antibody","description":"\u003cp\u003eCalcium-activated substrate recognition component of the SCF (SKP1-cullin-F-box protein) E3 ubiquitin-protein ligase complex, SCF(FBXL2), which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Unlike many F-box proteins, FBXL2 does not seem to target phosphodegron within its substrates but rather calmodulin-binding motifs and is thereby antagonized by calmodulin. This is the case for the cyclins CCND2 and CCND3 which polyubiquitination and subsequent degradation are inhibited by calmodulin.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58161281499476,"sku":"ABM417393-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58161281532244,"sku":"ABM417393-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58161281565012,"sku":"ABM417393-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/de\/products\/rabbit-polyclonal-antibody-to-fbxl2-p34612","provider":"ABMIUM","version":"1.0","type":"link"}