{"product_id":"rabbit-polyclonal-antibody-to-dbc1-phospho-thr454-p44472","title":"Anti-DBC1 (phospho-Thr454) Rabbit Polyclonal Antibody","description":"\u003cp\u003e\u003cstrong\u003eCCAR2\u003c\/strong\u003e is a core component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation with the regulation of alternative splicing: the DBIRD complex affects local transcript elongation rates and alternative splicing of a large set of exons embedded in (A + T)-rich DNA regions. CCAR2 inhibits SIRT1 deacetylase activity leading to increasing levels of p53\/TP53 acetylation and p53-mediated apoptosis. CCAR2 inhibits SUV39H1 methyltransferase activity.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58168137646420,"sku":"ABM420961-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58168137679188,"sku":"ABM420961-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58168137711956,"sku":"ABM420961-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/de\/products\/rabbit-polyclonal-antibody-to-dbc1-phospho-thr454-p44472","provider":"ABMIUM","version":"1.0","type":"link"}