{"product_id":"rabbit-polyclonal-antibody-to-cullin-2-p41795","title":"Anti-Cullin 2 Rabbit Polyclonal Antibody","description":"\u003cp\u003e\u003cstrong\u003eCUL2\u003c\/strong\u003e is a core component of multiple cullin-RING-based ECS (ElonginB\/C-CUL2\/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of target proteins. CUL2 serves as a rigid scaffold in the complex and may contribute to catalysis through positioning of the substrate and the E2 ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cullin subunit with TIP120A\/CAND1.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58162599199060,"sku":"ABM418914-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58162599231828,"sku":"ABM418914-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58162599264596,"sku":"ABM418914-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/de\/products\/rabbit-polyclonal-antibody-to-cullin-2-p41795","provider":"ABMIUM","version":"1.0","type":"link"}