{"product_id":"rabbit-polyclonal-antibody-to-crlf1-p31734","title":"Anti-CRLF1 Rabbit Polyclonal Antibody","description":"\u003cp\u003e\u003cstrong\u003eCRLF1\u003c\/strong\u003e functions as secretory protein carrier chaperone that promotes cellular release. Also functions as a cytokine subunit within the CRLF1-CLCF1 heterodimer, which engages the CNTF receptor complex (CNTFR, IL6ST\/gp130, LIFR). As part of the CRLF-CLCF1 complex, binds to CNTFR, induces dimerization of the IL6ST\/gp130 and LIFR, which activates JAK tyrosine kinases (JAK1 or JAK2 and to lesser extent TYK2) bound to their intracellular domains.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58035473154388,"sku":"ABM414899-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58035473187156,"sku":"ABM414899-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58035473219924,"sku":"ABM414899-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/de\/products\/rabbit-polyclonal-antibody-to-crlf1-p31734","provider":"ABMIUM","version":"1.0","type":"link"}