{"product_id":"rabbit-polyclonal-antibody-to-cdk11a-cdk11b-p42920","title":"Anti-CDK11A\/CDK11B Rabbit Polyclonal Antibody","description":"\u003cp\u003eCyclin-dependent protein kinase that acts as a regulator of transcription and pre-mRNA splicing. CDK11B acts as a key regulator of pre-mRNA splicing by mediating phosphorylation of SF3B1, enabling the association between SF3B1 and U5 and U6 snRNAs in the activated spliceosome, thereby promoting spliceosome assembly. Also acts as a regulator of transcription by phosphorylating 'Ser-2' of the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAP II) POLR2A.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58167107158356,"sku":"ABM419894-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58167107191124,"sku":"ABM419894-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58167107223892,"sku":"ABM419894-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/de\/products\/rabbit-polyclonal-antibody-to-cdk11a-cdk11b-p42920","provider":"ABMIUM","version":"1.0","type":"link"}