{"product_id":"rabbit-polyclonal-antibody-to-c-cbl-ab-700-p41567","title":"Anti-c-Cbl(Ab-700) Rabbit Polyclonal Antibody","description":"\u003cp\u003e\u003cstrong\u003eCBL\u003c\/strong\u003e is an E3 ubiquitin-protein ligase that acts as a negative regulator of many signalling pathways by mediating ubiquitination of cell surface receptors. Accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome. CBL recognizes activated receptor tyrosine kinases, including KIT, FLT1, FGFR1, FGFR2, PDGFRA, PDGFRB, CSF1R, EPHA8 and KDR and mediates their ubiquitination to terminate signalling.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58162467635540,"sku":"ABM418740-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58162467668308,"sku":"ABM418740-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58162467701076,"sku":"ABM418740-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/de\/products\/rabbit-polyclonal-antibody-to-c-cbl-ab-700-p41567","provider":"ABMIUM","version":"1.0","type":"link"}