{"product_id":"rabbit-polyclonal-antibody-to-atf4-p07124","title":"Anti-ATF4 Rabbit Polyclonal Antibody","description":"\u003cp\u003e\u003cstrong\u003eATF4\u003c\/strong\u003e is a transcription factor that binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3') and displays two biological functions, as regulator of metabolic and redox processes under normal cellular conditions, and as master transcription factor during integrated stress response (ISR). ATF4 binds to asymmetric CRE's as a heterodimer and to palindromic CRE's as a homodimer. Core effector of the ISR, which is required for adaptation to various stress such as endoplasmic reticulum (ER) stress, amino acid starvation, mitochondrial stress or oxidative stress.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58006660481364,"sku":"ABM403003-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58006660514132,"sku":"ABM403003-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58006660546900,"sku":"ABM403003-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/de\/products\/rabbit-polyclonal-antibody-to-atf4-p07124","provider":"ABMIUM","version":"1.0","type":"link"}