{"product_id":"rabbit-polyclonal-antibody-to-abca2-p32927","title":"Anti-ABCA2 Rabbit Polyclonal Antibody","description":"\u003cp\u003e\u003cstrong\u003eABCA2\u003c\/strong\u003e is thought to function as a lipid transporter that modulates cholesterol sequestration in the late endosome\/lysosome by regulating the intracellular sphingolipid metabolism, in turn participates in cholesterol homeostasis. ABCA2 may alter the transbilayer distribution of ceramide in the intraluminal membrane lipid bilayer, favoring its retention in the outer leaflet that results in increased acid ceramidase activity in the late endosome\/lysosome, facilitating ceramide deacylation to sphingosine leading to the sequestration of free cholesterol in lysosomes.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58156497961300,"sku":"ABM415889-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58156497994068,"sku":"ABM415889-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58156498026836,"sku":"ABM415889-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/de\/products\/rabbit-polyclonal-antibody-to-abca2-p32927","provider":"ABMIUM","version":"1.0","type":"link"}