{"product_id":"rabbit-monoclonal-antibody-to-presenilin-2-p20838","title":"Anti-Presenilin 2 Rabbit Monoclonal Antibody","description":"\u003cp\u003eCatalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyses the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein). Selectively cleaves late endosomal\/lysosomal localized substrates and generates the prominent pool of intracellular amyloid beta that contains longer amyloid beta. The holoprotein functions as a calcium-leak channel that allows the passive movement of calcium from endoplasmic reticulum to cytosol and is involved in calcium homeostasis.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58019829711188,"sku":"ABM410954-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58019829743956,"sku":"ABM410954-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58019829776724,"sku":"ABM410954-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/de\/products\/rabbit-monoclonal-antibody-to-presenilin-2-p20838","provider":"ABMIUM","version":"1.0","type":"link"}