{"product_id":"proteogenix-cd40-recombinant-protein","title":"CD40 Recombinant Protein","description":"\u003ch2\u003eGeneral information on CD40 Recombinant Protein:\u003c\/h2\u003e \u003cp\u003e CD40, also known as TNFRSF5, is a member of the TNF receptor superfamily, which is a single transmembrane glycoprotein. The CD40 protein plays a vital role in mediating a variety of immune and inflammatory responses, including the change in class T that depends on the type of immunoglobulin, the development of B cell memory and the formation of reproductive centers. The CD40 protein is expressed in B cells, dendritic cells, macrophages, endothelial cells and some tumor cells. CD40 deficiency can lead to high IgM type 3 (HIGM3) immunodeficiency. In addition, β-amyloid-induced microglia activation requires CD40 \/ CD40L interaction and is therefore considered an early event in the pathogenesis of Alzheimer’s disease.\u003c\/p\u003e\u003cp\u003eProteoGenix catalogue number PX-P4082. For research use only.\u003c\/p\u003e\u003cp\u003eHost: Mammalian cells; Expression system: Eukaryotic expression; Purity: \u0026gt;90% by SDS-PAGE; Molecular weight: 22.32kDa; Tag: C-terminal His Tag; Fragment: Met1~Arg193; Buffer: PBS pH7.5; Applications: ELISA, WB.\u003c\/p\u003e\u003cp\u003eAvailable configurations: 50ug, 100ug, 1mg.\u003c\/p\u003e\u003cp\u003e\u003ca href=\"https:\/\/www.proteogenix.science\/wp-content\/uploads\/documents\/Datasheets\/PX-P4082.pdf\"\u003eDownload the manufacturer datasheet\u003c\/a\u003e\u003c\/p\u003e","brand":"ProteoGenix","offers":[{"title":"50ug","offer_id":57376169034068,"sku":"ABM146378-1","price":247.2,"currency_code":"GBP","in_stock":true},{"title":"100ug","offer_id":57376169066836,"sku":"ABM146378-2","price":335.2,"currency_code":"GBP","in_stock":true},{"title":"1mg","offer_id":57376169099604,"sku":"ABM146378-3","price":988.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/bioactivity-validation-cd40-recombinant-protein.jpg?v=1790896516","url":"https:\/\/www.abmium.com\/de\/products\/proteogenix-cd40-recombinant-protein","provider":"ABMIUM","version":"1.0","type":"link"}