{"product_id":"proteogenix-cd272-recombinant-protein","title":"CD272 Recombinant Protein","description":"\u003ch2\u003e General Information about CD272 Recombinant Protein \u003ch2\u003e \u003c\/h2\u003e\n\u003c\/h2\u003e\u003cp\u003eCD272 (cluster of differentiation 272) is also designated as BTLA. BTLA expression is induced during T cell activation and BTLA is still expressed on Th1 cells instead of Th2 cells. Like PD1 and CTLA4, BTLA interacts with homologs B7 and B7H4. However, unlike PD-1 and CTLA-4, BTLA exhibits an inhibitory effect on T lymphocytes by interacting with familial neurotic tumor receptors (TNF-R), not just with cell surface receptors. Family interaction. BTLA is a linker of tumor necrosis factor 14 superfamily member (receptor) (TNFRSF14) and is also known as herpes virus mediator (HVEM). The BTLA-HVEM complex negatively regulates the immune response of T cells. Activation of BTLA inhibits the function of cancer-specific human CD8 + T cells.\u003c\/p\u003e\u003cp\u003eProteoGenix catalogue number PX-P4114. For research use only.\u003c\/p\u003e\u003cp\u003eHost: Mammalian cells; Expression system: Eukaryotic expression; Purity: \u0026gt;90% by SDS-PAGE; Molecular weight: 32kDa; Tag: C-terminal His Tag; Fragment: Met1~Ser150; Buffer: PBS pH7.5; Applications: WB, ELISA.\u003c\/p\u003e\u003cp\u003eAvailable configurations: 50ug, 100ug, 1mg.\u003c\/p\u003e\u003cp\u003e\u003ca href=\"https:\/\/www.proteogenix.science\/wp-content\/uploads\/documents\/Datasheets\/PX-P4114.pdf\"\u003eDownload the manufacturer datasheet\u003c\/a\u003e\u003c\/p\u003e","brand":"ProteoGenix","offers":[{"title":"50ug","offer_id":57376231620948,"sku":"ABM146390-1","price":164.0,"currency_code":"GBP","in_stock":true},{"title":"100ug","offer_id":57376231653716,"sku":"ABM146390-2","price":239.2,"currency_code":"GBP","in_stock":true},{"title":"1mg","offer_id":57376231686484,"sku":"ABM146390-3","price":692.0,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/de\/products\/proteogenix-cd272-recombinant-protein","provider":"ABMIUM","version":"1.0","type":"link"}