{"product_id":"proteogenix-anti-dog-cd22-polyclonal-antibody","title":"Anti-Dog CD22 Polyclonal Antibody","description":"\u003cp\u003eAnti-Dog CD22 Polyclonal Antibody\u003c\/p\u003e \u003cp\u003eThe Anti-Dog CD22 Polyclonal Antibody is a high-quality research tool specifically designed for the detection and analysis of CD22 protein in canine samples. CD22, also known as Siglec-2, is a transmembrane glycoprotein that is primarily expressed on the surface of B cells. This protein plays a crucial role in regulating B cell activation and survival, making it a valuable target for research in the field of immunology and cancer biology.\u003c\/p\u003e \u003cp\u003eThis polyclonal antibody is produced in rabbits using a highly purified recombinant CD22 protein as the immunogen. It has been extensively validated for its specificity and sensitivity in various assays, including Western blotting, immunohistochemistry, and flow cytometry. The Anti-Dog CD22 Polyclonal Antibody has been shown to specifically recognize the CD22 protein in a variety of canine tissues and cell lines, making it a reliable tool for canine research.\u003c\/p\u003e \u003cp\u003eOne of the main applications of this antibody is in the study of B cell-related diseases, such as B cell lymphomas and leukemias. CD22 is known to be overexpressed in these types of cancers, and targeting it with specific antibodies has shown promising results in preclinical studies. The Anti-Dog CD22 Polyclonal Antibody can be used to investigate the role of CD22 in these diseases and potentially aid in the development of new therapeutic strategies.\u003c\/p\u003e \u003cp\u003eIn addition to cancer research, this antibody can also be used in studies of autoimmune disorders. CD22 has been linked to the regulation of autoreactive B cells, and its dysfunction has been associated with autoimmune diseases such as rheumatoid arthritis and systemic lupus erythematosus. The Anti-Dog CD22 Polyclonal Antibody can help researchers better understand the role of CD22 in these conditions and potentially identify new targets for treatment.\u003c\/p\u003e \u003cp\u003eExperimental use cases for this antibody include the detection of CD22 expression in canine tumor samples, the evaluation of CD22-targeted therapies in preclinical models, and the investigation of CD22-mediated signaling pathways in B cells. Its high specificity and sensitivity make it a valuable tool for these and other research applications.\u003c\/p\u003e \u003cp\u003eIn summary, the Anti-Dog CD22 Polyclonal Antibody is a reliable and specific tool for the detection and analysis of CD22 protein in canine samples. With its potential applications in cancer research and autoimmune disorders, this antibody is a valuable addition to any biotech laboratory. Order now and advance your research with confidence.\u003c\/p\u003e\u003cp\u003eProteoGenix catalogue number ARO-A22094. For research use only.\u003c\/p\u003e\u003cp\u003eTarget: B-cell receptor CD22 isoform X1; CD22; Clonality: Polyclonal Antibody; Reactivity: Dog; Applications: IHC, ELISA.\u003c\/p\u003e\u003cp\u003eAvailable configurations: 50ug, 100ug, 1mg.\u003c\/p\u003e\u003cp\u003e\u003ca href=\"https:\/\/www.proteogenix.science\/wp-content\/uploads\/documents\/Datasheets\/ARO-A22094.pdf\"\u003eDownload the manufacturer datasheet\u003c\/a\u003e\u003c\/p\u003e","brand":"ProteoGenix","offers":[{"title":"50ug","offer_id":57353739501908,"sku":"ABM121674-1","price":140.0,"currency_code":"GBP","in_stock":true},{"title":"100ug","offer_id":57353739534676,"sku":"ABM121674-2","price":215.2,"currency_code":"GBP","in_stock":true},{"title":"1mg","offer_id":57353739567444,"sku":"ABM121674-3","price":671.2,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Primaryantibodies-CCt9H6Tc_b08459a7-d3fb-472f-957e-6836270f5242.svg?v=1790886028","url":"https:\/\/www.abmium.com\/de\/products\/proteogenix-anti-dog-cd22-polyclonal-antibody","provider":"ABMIUM","version":"1.0","type":"link"}