{"product_id":"abm217186","title":"Human N-lysine Methyltransferase Smyd2, SMYD2 ELISA Kit","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eProtein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53\/TP53 and RB1. Specifically trimethylates histone H3 'Lys-4' (H3K4me3) in vivo. The activity requires interaction with HSP90alpha. Shows even higher methyltransferase activity on p53\/TP53. Monomethylates 'Lys-370' of p53\/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53\/TP53. Monomethylates RB1 at 'Lys-860'.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"48T","offer_id":57661803823444,"sku":"ABM217186","price":205.0,"currency_code":"GBP","in_stock":true},{"title":"96T","offer_id":57661803856212,"sku":"ABM217187","price":293.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-dd2fcfbe1faad6212582bfea276fa812b0e24646924cfe4605ca957d0fc75c6c.jpg?v=1792159220","url":"https:\/\/www.abmium.com\/de\/products\/abm217186","provider":"ABMIUM","version":"1.0","type":"link"}