{"product_id":"abm216342","title":"Human Endoplasmic Reticulum Aminopeptidase 1, ERAP1 ELISA Kit","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eAminopeptidase that plays a central role in Peptide trimming, a step required for the generation of most HLA class I-binding Peptides. Peptide trimming is essential to customize longer precursor Peptides to fit them to the correct length required for presentation on MHC class I molecules. Strongly prefers substrates 9-16 residues long. Rapidly degrades 13-mer to a 9-mer and then stops. Preferentially hydrolyzes the residue Leu and Peptides with a hydrophobic C-terminus, while it has weak activity toward Peptides with charged C-terminus. May play a role in the inactivation of Peptide hormones. May be involved in the regulation of blood pressure through the inactivation of angiotensin II and\/or the generation of bradykinin in the kidney.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"48T","offer_id":57661673636180,"sku":"ABM216342","price":205.0,"currency_code":"GBP","in_stock":true},{"title":"96T","offer_id":57661673668948,"sku":"ABM216343","price":293.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-2e3c133bfbe32a47ca7a83618e6e715eac2d1109fe10cd647ba3be4c4d83991a.jpg?v=1792159209","url":"https:\/\/www.abmium.com\/de\/products\/abm216342","provider":"ABMIUM","version":"1.0","type":"link"}