{"product_id":"abm216266","title":"Human DNA Replication Licensing Factor Mcm7, MCM7 ELISA Kit","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eActs as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for S-phase checkpoint activation upon UV-induced damage.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"48T","offer_id":57661609673044,"sku":"ABM216266","price":205.0,"currency_code":"GBP","in_stock":true},{"title":"96T","offer_id":57661609705812,"sku":"ABM216267","price":293.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-8666f1e1fdfe95315f7fc405479ad1ea714285ff298c31ad7fc4f20cc586f0a8.jpg?v=1792159204","url":"https:\/\/www.abmium.com\/de\/products\/abm216266","provider":"ABMIUM","version":"1.0","type":"link"}