{"product_id":"abm215900","title":"Human Agouti-signaling Protein, ASIP ELISA Kit","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eInvolved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown\/black pigment) and thus increasing synthesis of pheomelanin (yellow\/red pigment). In higher primates, agouti may affect the quality of hair pigmentation rather than its pattern of deposition. Could well play a role in neuroendocrine aspects of melanocortin action. May have some functional role in regulating the lipid metabolism with adipocytes.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"48T","offer_id":57661827940692,"sku":"ABM215900","price":205.0,"currency_code":"GBP","in_stock":true},{"title":"96T","offer_id":57661827973460,"sku":"ABM215901","price":293.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-4a820749d2e7ebca58e949ff8c89c1df7a3c1b44ac24fdc4b18d957540956f21.jpg?v=1792159227","url":"https:\/\/www.abmium.com\/de\/products\/abm215900","provider":"ABMIUM","version":"1.0","type":"link"}