{"product_id":"abm214228","title":"Human Mucolipin 2, MCOLN2 ELISA Kit","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eNonselective cation Channel probably playing a role in the regulation of membrane trafficking events. Acts as Ca(2+)-permeable cation Channel with inwardly rectifying activity (PubMed: 19940139, PubMed: 19885840). May activate ARF6 and be involved in the trafficking of GPI-anchored cargo proteins to the cell surface via the ARF6-regulated recycling pathway (PubMed: 17662026). May play a role in immune processes. In adaptive immunity, TRPML2 and TRPML1 may play redundant roles in the function of the specialized lysosomes of B cells (By similarity). In the innate immune response, may play a role in the regulation of chemokine secretion and macrophage migration (By similarity). Through a possible and probably tissue-specific heteromerization with MCOLN1 may be at least in part involved in many lysosome-dependent cellular events (PubMed: 19885840).\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"48T","offer_id":57662003577172,"sku":"ABM214228","price":205.0,"currency_code":"GBP","in_stock":true},{"title":"96T","offer_id":57662003609940,"sku":"ABM214229","price":293.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-da19a9396bf0d47379b549b3ba16ba2db03e8f334960870f1d499cfc096995c7.jpg?v=1792159211","url":"https:\/\/www.abmium.com\/de\/products\/abm214228","provider":"ABMIUM","version":"1.0","type":"link"}