{"product_id":"abm212946","title":"Human Frizzled-10, FZD10 ELISA Kit","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eReceptor for Wnt proteins. Functions in the canonical Wnt\/beta-catenin signaling pathway (By similarity). The canonical Wnt\/beta-catenin signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and\/or in differentiated tissues (Probable).\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"48T","offer_id":57662070915412,"sku":"ABM212946","price":205.0,"currency_code":"GBP","in_stock":true},{"title":"96T","offer_id":57662070948180,"sku":"ABM212947","price":293.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-37ecc0ddd2a79f53656445e745bece8d7e1326a1938acf20aff7fe2b79f2a155.jpg?v=1792159216","url":"https:\/\/www.abmium.com\/de\/products\/abm212946","provider":"ABMIUM","version":"1.0","type":"link"}