{"product_id":"abm210788","title":"Human Apelin Receptor, APLNR ELISA Kit","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eReceptor for apelin receptor early endogenous ligand (APELA) and apelin (APLN) hormones coupled to G proteins that inhibit adenylate cyclase activity (PubMed: 11090199, PubMed: 25639753, PubMed: 28137936). Plays a key role in early development such as gastrulation, blood vessels formation and heart morphogenesis by acting as a receptor for APELA hormone (By similarity). May promote angioblast migration toward the embryonic midline, i.e. the position of the future vessel formation, during vasculogenesis (By similarity). Promotes sinus venosus (SV)-derived endothelial cells migration into the developing heart to promote coronary blood vessel development (By similarity). Plays also a role in various processes in adults such as regulation of blood vessel formation, blood pressure, heart contractility and heart failure (PubMed: 25639753, PubMed: 28137936). (Microbial infection) Alternative coreceptor with CD4 for HIV-1 infection; may be involved in the development of AIDS dementia (PubMed: 11090199).\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"48T","offer_id":57661808968020,"sku":"ABM210788","price":205.0,"currency_code":"GBP","in_stock":true},{"title":"96T","offer_id":57661809000788,"sku":"ABM210789","price":293.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-8fa625525f6e1015ae8a8b9394d1c02d8e12d9a0917e51504128bd89d34b9fea.jpg?v=1792159208","url":"https:\/\/www.abmium.com\/de\/products\/abm210788","provider":"ABMIUM","version":"1.0","type":"link"}