{"product_id":"abm210584","title":"Human Rho-related GTP-binding Protein Rhob(Rhob), RHOB ELISA Kit","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eMediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellular protein trafficking of a number of proteins. Targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1\/AKT which promotes endothelial cell survival during vascular development. Serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Required for genotoxic stress-induced cell death in breast cancer cells.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"48T","offer_id":57661673963860,"sku":"ABM210584","price":205.0,"currency_code":"GBP","in_stock":true},{"title":"96T","offer_id":57661673996628,"sku":"ABM210585","price":293.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-0ff8a88de4a865718eb8092a323732a847ba7914e23506aa7f35e4fff43c3523.jpg?v=1792159245","url":"https:\/\/www.abmium.com\/de\/products\/abm210584","provider":"ABMIUM","version":"1.0","type":"link"}