{"product_id":"abm209992","title":"Rat Mothers Against Decapentaplegic Homolog 2, SMAD2 ELISA Kit","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eReceptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2\/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator (By similarity).\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"48T","offer_id":57661785276756,"sku":"ABM209992","price":205.0,"currency_code":"GBP","in_stock":true},{"title":"96T","offer_id":57661785309524,"sku":"ABM209993","price":293.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-3027bac3c1ae20499ebfc938c9fa86f81ef4156b4784bf60bc0a49a76b91c4a8.jpg?v=1792159252","url":"https:\/\/www.abmium.com\/de\/products\/abm209992","provider":"ABMIUM","version":"1.0","type":"link"}