{"product_id":"abm209666","title":"Rat Cyclin-dependent kinase inhibitor 1, CDKN1A ELISA Kit","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eMay be the important intermediate by which p53\/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression. Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1. At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"48T","offer_id":57662036967764,"sku":"ABM209666","price":205.0,"currency_code":"GBP","in_stock":true},{"title":"96T","offer_id":57662037000532,"sku":"ABM209667","price":293.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-d6953ddafcb2478356c2506e9088404987e53032e0e65992f749303ff664fa55.jpg?v=1792159227","url":"https:\/\/www.abmium.com\/de\/products\/abm209666","provider":"ABMIUM","version":"1.0","type":"link"}