{"product_id":"abm207098","title":"Phospho-AIP4 (Y420) Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eITCH (itchy E3 ubiquitin protein ligase) encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein plays a role in multiple cellular processes including erythroid and lymphoid cell differentiation and the regulation of immune responses. Mutations in ITCH are a cause of syndromic multisystem autoimmune disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for ITCH.\u003c\/p\u003e\u003cp\u003e\u003cem\u003ePackaging image shown for reference. Select a size from the available options.\u003c\/em\u003e\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57660776907092,"sku":"ABM207098","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57660776939860,"sku":"ABM207099","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57660776972628,"sku":"ABM207100","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-f324e8429e766fa1531f7fd366db4d43d637484a38050b0923e08284f225198b.jpg?v=1792157294","url":"https:\/\/www.abmium.com\/de\/products\/abm207098","provider":"ABMIUM","version":"1.0","type":"link"}