{"product_id":"abm206555","title":"GAPDH Monoclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eGlyceraldehyde-3-phosphate dehydrogenase (GAPDH) is well known as one of the key enzymes involved in glycolysis. It catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The enzyme exists as a tetramer of identical chains. Besides its functioning as a glycolytic enzyme in cytoplasm, recent evidence suggest that mammalian GAPDH is also involved in a great number of intracellular proceses such as membrane fusion, microtubule bundling, phosphotransferase activity, nuclear RNA export, DNA replication, and DNA repair. During the last decade a lot of findings appeared concerning the role of GAPDH in different pathologies including prostate cancer progression, programmed neuronal cell death, age- related neuronal diseases, such as Alzheimer\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"100μL","offer_id":57661324886356,"sku":"ABM206555","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"50μL","offer_id":57661324919124,"sku":"ABM206556","price":77.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-ee599e8d3717d0e3a7bed80049ee049f98c8f424802d45604d71663118c3014e.jpg?v=1792159156","url":"https:\/\/www.abmium.com\/de\/products\/abm206555","provider":"ABMIUM","version":"1.0","type":"link"}