{"product_id":"abm205987","title":"MRE11 Monoclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThis gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"100μL","offer_id":57661424632148,"sku":"ABM205987","price":205.0,"currency_code":"GBP","in_stock":true},{"title":"50μL","offer_id":57661424664916,"sku":"ABM205988","price":141.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-23bb6750c29a78cca668569ce44109696454668dec6e1857a8257b2c8cd07a9e.jpg?v=1792159111","url":"https:\/\/www.abmium.com\/de\/products\/abm205987","provider":"ABMIUM","version":"1.0","type":"link"}