{"product_id":"abm205745","title":"SIGLEC8 Monoclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eSialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM; MIM 603492) that mediates an association with SLAM-associated protein (SAP; MIM 300490) (summarized by Foussias et al., 2000 [PubMed 11095983])\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"100μL","offer_id":57661196173652,"sku":"ABM205745","price":205.0,"currency_code":"GBP","in_stock":true},{"title":"50μL","offer_id":57661196206420,"sku":"ABM205746","price":141.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-b2e87ca805cb6d330c5bc6ecc74e853b0b62a0c431ed97eb0c41f8b4c9ee88bb.jpg?v=1792159121","url":"https:\/\/www.abmium.com\/de\/products\/abm205745","provider":"ABMIUM","version":"1.0","type":"link"}