{"product_id":"abm205585","title":"TNFSF9 Monoclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThe protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9\/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9\/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene, TNFSF9\/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"100μL","offer_id":57661042819412,"sku":"ABM205585","price":205.0,"currency_code":"GBP","in_stock":true},{"title":"50μL","offer_id":57661042852180,"sku":"ABM205586","price":141.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-672db92a2ed94b82bc55c38ea2e53de094624a4d14caf72452e36bd469d01f1d.jpg?v=1792159087","url":"https:\/\/www.abmium.com\/de\/products\/abm205585","provider":"ABMIUM","version":"1.0","type":"link"}