{"product_id":"abm204401","title":"CD86 Monoclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThis gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined.Tissue specificity: Expressed by activated B-lymphocytes and monocytes.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"100μL","offer_id":57661568549204,"sku":"ABM204401","price":205.0,"currency_code":"GBP","in_stock":true},{"title":"50μL","offer_id":57661568581972,"sku":"ABM204402","price":141.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-822a3bfaa4b55fb1d773d161a0a8bfd3979acbdba59f3606c1c23a8b923c0698.jpg?v=1792159149","url":"https:\/\/www.abmium.com\/de\/products\/abm204401","provider":"ABMIUM","version":"1.0","type":"link"}