{"product_id":"abm203879","title":"EIF4E Monoclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eeIF4E, a protein modulates translation of maternal mRNAs in early embryos before the onset of zygotic transcription. eIF4E also influences the overall rate of translation. eIF4E binds to the 7 methyl GTP cap structure of eukaryotic mRNAs. Phosphorylation of eIF4E on serine 209 regulates the affinity of this protein for the 7 methyl GTP cap and\/or RNA. Phosphorylation also enhances the interaction of eIF4E with eIF4G, which form a complex known as eIF4F. eIF4E phosphorylation is correlated with increased translational rate in a number of cell types. Several kinases are currently being investigated as potential regulators of eIF4E including PKC and\/or the MAP kinase activated Mnk.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"100μL","offer_id":57661035020628,"sku":"ABM203879","price":205.0,"currency_code":"GBP","in_stock":true},{"title":"50μL","offer_id":57661035053396,"sku":"ABM203880","price":141.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-206241b1573a3d176fa83b7af4309c24eba100af838d4a3aedaee457c29b1376.jpg?v=1792159122","url":"https:\/\/www.abmium.com\/de\/products\/abm203879","provider":"ABMIUM","version":"1.0","type":"link"}